ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (6): 1209-1214.doi: 10.11843/j.issn.0366-6964.2016.06.016

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Infectivity of Four H3N8 Avian Influenza Viruses of Duck Origin in SPF Chickens

CUI Peng-fei1,2,PENG Zhi 2,ZHANG Fang 2,GUAN Li-zheng 1,2,XIAO Li 2,LI Li-sha 2,DENG Guo-hua 2* ,CHEN Hua-lan 1,2*   

  1. (1.College of Veterinary Medicine,Gansu Agricultural University,Lanzhou 730070,China;2.Animal Influenza Laboratory of Ministry of Agriculture,State Key Laboratory of Veterinary Biotechnology,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150001,China)
  • Received:2016-03-01 Online:2016-06-23 Published:2016-06-23

Abstract:

In order to evaluate the infectious risk of H3N8 avian influenza viruses(AIV) of duck origin to chickens,four H3N8 AIV viruses with HA genes belonged to different genotypes were selected to challenge SPF chickens.It was demonstrated that the four viruses could infect chickens without pre-adaptation,and the four viruses had different replication capacity in chicken’s organs.After challenge,there weren’t obvious clinical symptoms in chickens,and most challenged chickens could shed viruses through orpharyngeal and cloacal routes.In addition,DK/ZJ/S4088/2013 and DK/GZ/S1245/2013 could transmit from infected chickens to healthy contact chickens.In conclusion,the four duck H3N8 AIV viruses in this study posed the potential risk to infect chickens and even could transmit among chickens,and measures should be taken to avoid the contact between chickens and ducks in the breeding and circulation of poultry.

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